共有50个其中有15个是秘密成就
 Mission Impossible 50
Complete the game on Zealot setting 
 Romper Stomper 25
Stomp 10 Containers 
 Vacuum Cleaner 30
Decompress 20 Necromorphs without getting sucked out yourself 
 Made Us Whole 10
Complete the game on any difficulty setting 
 Frozen in Time 10
Kill 50 Necromorphs while they are in Stasis (single player only) 
 First Aid 10
Use Quick Heal ten times (single player only) 
 Epic Dismemberment 50
Dismember 2,500 Necromorph Limbs (single player only) 
 ...And Stay Down 10
Kill 25 crawling enemies with Stomp (single player only) 
 Think Fast 15
Kill 30 Necromorphs with Kinesis objects 
 The Nanny 10
Kill 30 Crawlers without detonating them 
 C-Section 10
Knock down an enemy with Contact Beam Alt-Fire then kill it with Primary Fire before it stands up 
 Going for Distance 20
Impale an enemy and make him fly through the air for 17 meters - it must stick to the surface 
 Taste of your own Medicine 20
TK Impale a live Slasher to a surface using a Slashers arm - it must stick to the surface 
 Its a Trap! 20
Kill 20 enemies with Detonator Mines in a deployed state 
 Necro Flambé 10
Kill 50 enemies using the Flamethrower 
 Peek a Boo! 20
Kill a Stalker with the Seeker Rifle while in Zoom Mode 
 Brute Juke 10
Kill a Brute without taking damage 
 Shoot the Limbs! 10
Dismember 25 Necromorph Limbs (single player only) 
 Bouncing Betty 10
Kill a Cyst by catching its Mine and throwing it back 
 Skewered in Space 15
Impale an enemy into a Decompression Window to cause it to blow out 
 Hard to the Core 50
Complete the game on Hard Core setting 
 Clean Cut 10
Sever all three tentacles of a Lurker with one Line Gun Primary Fire shot (single player only) 
 Lawnmower Man 10
Kill 4 enemies with the same Ripper blade 
 Fully Loaded 50
Simultaneously have four completely upgraded weapons 
 The Sampler Platter 20
Kill a Necromorph with every Weapon in the game (single player only). 
 Lightspeed de Milo 10
Dismember the Lightspeed Boy Statue 
 Looking good 10
Purchase the Advanced Suit 
 Fully Outfitted 30
Upgrade your RIG and Stasis completely 
 Picking favorites 30
Upgrade 1 Weapon completely 
 The Engineer 10
Collect 10 Schematics 
 My Boom Stick 20
Kill 6 enemies at once with Line Guns Alt-Fire (single player only) 
 Shock Therapy 10
Impale an enemy with the Javelin Gun and use its Alt-Fire to shock 3 others (single player only) 
 Collect Peng 20
Find the Peng treasure (1)
 The Librarian 10
Collect 100 logs 
 The Electrician 10
Collect 10 Semiconductors